At winter limited, I splashed 1 thresh elitism for 4 cards (Runivoltaic Accumulator, 2 Runic Reinforcement and 1 P3pp3r 0f 1n54n17y)... and the faction. The H07 P3pp3r is actually a bad example. It's an amazing card, but anytime you start with 1 elitism, you gain the ability to play the Alliance of Handy Weirdoes. That's a huge advatange. Period. I might consider splashing for just a H07 P3pp3r because of the unbalancing effect that the Alliance can have on games, but maybe that's just me. Normally, though, I won't splash 1 thresh for less than 4 good cards (say, a Horrendous Behemoth, 2 Hamsters and an Encumber).
Edit: Oh, or if I have like 3 Karmic Cakes and can play 1 of the resource in deck along with 2 or 3 good 1 thresh cards..
The Gnomish One: Cracking Heist Planners in sealed since 2006.
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The Garbageman can because he mixes it with love and makes the world smell goooood.